|
|
Women: Find a local Professional who
carries Professionals: Log-On
To Reorder |
|||||
|
|
||||||
|
Home | Symptoms & Risks | Ask A Doctor
| Q & A Library | Find a Physician | Choose a Pharmacist | Site Map |
||||||
|
|
||||||
|
A Synergistically Designed Menopause Type® Formulation |
Formulation Focus |
|||||
|
|
testo-calm™ |
|
||||
|
A Unique Blend of Phytoantiandrogens |
||||||
|
Designed for women with menopause symptoms associated with excessive testosterone function, such as Menopause Types® 3, 6, 9 & 12.♦ |
||||||
|
How Women Will Benefit From testo-Calm™ |
||||||
|
||||||
|
||||||
|
||||||
|
||||||
|
||||||
|
||||||
|
|
||||||
|
Synergistic Formulation: |
||||||
|
testo-Calm™ is a synergistic designed formula
developed to promote healthy hormone balance in women by calming and supporting
the ideal function of testosterone sensitive tissues. (Excessive affects of
the hormone testosterone in women is associated with hirsutism, acne,
androgenic alopecia as well as mood changes, insulin resistance, elevated blood lipids and increased risk of breast,
endometrial and possibly other cancers. The affect may be due to either androgen
excess or increased sensitivity to normal levels of androgens.)♦ |
||||||
|
Decreasing the sensitivity to excessive androgen levels
can support the healthy function of skin, hair, heart, breasts, vagina and
other testosterone sensitive tissues and may promote optimal structure and
function of these tissues, which can result in an improvement of
perimenopause, menopause and postmenopause symptoms.♦ |
||||||
|
Three Capsules Provide: |
||||||
|
testo-calm™ Herbal Blend |
2,160 mg |
|||||
|
(propriety blend of Saw Palmetto (berry,
standardized to 25% fatty acids), Fennel (Foeniculum vulgare,
seed), Nettles (leaf, standardized to 1% plant silica), Ocimum sanctum (leaf), Trigonella foenum-graecum (seed)
and Pygeum africanum (bark,
standardized to 12% phytosterols) |
||||||
|
Suggested Use: |
90
Capsules |
|||||
|
As a dietary supplement, adults take 3 capsules each morning
with food or as directed by physician. |
||||||
|
|
||||||
|
ABOUT
Phytoantiandrogens: Phytoantiandrogens are a class of phyto-compounds
that decrease tissue sensitivity to androgens or decrease androgen activity,
predominantly through the action of 5-alpha-reductase
inhibition, which decreases conversion of testosterone to the more androgenic
dihydrotestosterone. Androgen excess symptoms have been observed in
Menopause Types® 3, 6, 9 & 12. Androgen excess disorders have
also been observed in polycystic ovary disease (PCO) and PCO-like syndrome,
which has a milder clinical presentation than PCO. Even though PCO &
PCO-like syndrome occur in young women, associated insulin resistance, lipid
disorders and cancer risks have also been observed, revealing that these factors
are not exclusively age related.♦ |
||||||
|
Saw
Palmetto: Saw Palmetto (Serenoa repens) is widely used for the
antiandrogenic properties attributed to it, which are most likely due to the
presence of beta-sitosterol, palmitic-acid
and stearic-acid, all of which have 5-alpha-reductase
inhibiting activity. The anti-inflammatory properties have recently
been noted in Serenoa repens may be associated with
its beneficial properties.♦ |
||||||
|
Fennel: Fennel (Foeniculum Vulgare)
seed is a source of the antiandrogens Palmetic acid and beta-sitosterol
active components within many antiandrogenic herbs. The androgen antagonist properties of Foeniculum Vulgare have been used for women in topical agents to
control hirsutism. In animal studies, fennel extracts have demonstrated
antitumor activity in testosterone sensitive tissue.♦ |
||||||
|
Nettles: Nettles (Urtica dioica) has the antiandrogen
palmetic acid as an active component within the
herb. Antihyperglycemic and hypoglycemic effects have also been
noted in Urtica
dioica.
Anti-inflammatory, analgesic and antioxidant properties have been attributed
to Urtica dioca which
contribute to its beneficial properties.♦ |
||||||
|
Holy Basil: Holy Basil (Ocimum sanctum) leaf, with a long history of use in Ayurvedic
Medicine, contains antiandrogenic
properties that may be attributed to the presence of the 5-alpha-reductase inhibiting constituents; beta-sitosterol, palmitic-acid and stearic-acid. In animal studies the
anti-androgenic property of Ocimum Sanctum was
shown to diminish response in androgen sensitive tissues, an effect that was
reversible two weeks after the extract was stopped. Antihyperglycemic and
hypoglycemic effects has also been noted in Holy Basil. Animal studies
have shown Ocimum sanctum can cause lowering in
serum total cholesterol, triglyceride, phospholipid
and LDL-cholesterol levels and an increase in the HDL-cholesterol. Sedative
properties have been identified in Ocimum sanctum
as well as adaptogenic and antistressor properties in regard to adverse
stimuli and toxic substances. Ocimum sanctum has
also been found to inhibit acute as well as chronic inflammation in animal
studies, which may contribute to its antistress, adaptogenic properties.♦ |
||||||
|
Fenugreek: Fenugreek (Trigonella foenum-graecum)
seed has antiandrogenic
properties due to the presence of beta-sitosterol, palmitic-acid and stearic-acid. Beneficial anti-hyperglycemic
and hypoglycemic properties of Trigonella Foenum-Graecum have been shown to decrease elevated
glucose in a double blind placebo
controlled human study. It has been shown to reduce excessive glucose
levels and increase the number of insulin receptors in humans, possible by
stimulating glucose-dependent insulin secretion from pancreatic beta cells.
Both human and animal studies have shown Fenugreek has the ability to lower
total cholesterol, LDL, VLDL cholesterol and triglycerides significantly.
Anti-inflammatory properties have also been documented in Trigonella
Foenum Graecum,
contributing to its beneficial properties.♦ |
||||||
|
Pygeum: Pygeum (Pygeum africanum) bark has the antiandrogen beta-sitosterol.
Anti-inflammatory
properties have been noted in Pygeum Africanum contributing to the beneficial properties.♦ |
||||||
|
|
||||||
|
References: |
||||||
|
Ahmed
M, Ahamed RN, Aladakatti
RH, Ghosesawar MG. Reversible anti-fertility effect
of benzene extract of Ocimum sanctum leaves on
sperm parameters and fructose content in rats. J Basic Clin
Physiol Pharmacol. 2002;13(1):51-9. Ajabnoor MA, Tilmisany AK. Effect of Trigonella foenum graceum on blood glucose levels in normal and alloxan-diabetic mice. J Ethnopharmacol 1988; |
||||||
|
Anon.
1948-1976. The Wealth of India raw materials. Publications and Information
Directorate, CSIR, Breu W, Hagenlocher
M, Redl K, Tittel G, Stadler F, Wagner H. [Anti-inflammatory activity of sabal fruit extracts prepared with supercritical carbon
dioxide. In vitro antagonists of cyclooxygenase and
5-lipoxygenase metabolism] Arzneimittelforschung.
1992 Apr;42(4):547-51. German. Collins, JJ. 2002.
Discover Your Menopause Type. Prima Publishing Collins, Joseph J.
2002. Discover Your Menopause Type. Prima Publishing Duke, James A. 1992.
Handbook of phytochemical constituents of GRAS herbs and other economic
plants. Godhwani S, Godhwani
JL, Vyas DS. Ocimum
sanctum: an experimental study evaluating its anti-inflammatory, analgesic
and antipyretic activity in animals. J Ethnopharmacol.
1987 Nov;21(2):153-63. |
||||||
|
Gulcin I, Kufrevioglu
OI, Oktay M, Buyukokuroglu
ME. Antioxidant, antimicrobial, antiulcer and
analgesic activities of nettle (Urtica dioica L.). J Ethnopharmacol.
2004 Feb;90(2-3):205-15. Gupta A, Gupta R, Lal B. Effect of Trigonella
foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2
diabetes mellitus: a double blind placebo controlled study. J Assoc
Physicians Hannan JM, Rokeya B, Faruque O, Nahar N, Mosihuzzaman M, Azad Khan AK,
Ali L. Effect of soluble dietary fibre
fraction of Trigonella foenum
graecum on glycemic, insulinemic,
lipidemic and platelet aggregation status of Type 2
diabetic model rats. J Ethnopharmacol. 2003 Sep;88(1):73-7. |
||||||
|
Javidnia K, Dastgheib
L, Mohammadi Samani S, Nasiri A. Antihirsutism activity
of Fennel (fruits of Foeniculum vulgare)
extract. A double-blind placebo controlled study. Phytomedicine.
2003;10(6-7):455-8. Kelm MA, Nair MG, Strasburg GM, DeWitt DL.
Antioxidant and cyclooxygenase inhibitory phenolic compounds from Ocimum
sanctum Linn. Phytomedicine. 2000 Mar;7(1):7-13. |
||||||
|
Ng SS, Figg WD. Antitumor
activity of herbal supplements in human prostate cancer xenografts
implanted in immunodeficient mice. Anticancer Res. 2003
Sep-Oct;23(5A):3585-90. Paubert-Braquet M, Cave A, Hocquemiller R, Delacroix D, Dupont
C, Hedef N, Borgeat P.
Effect of Pygeum africanum
extract on A23187-stimulated production of lipoxygenase
metabolites from human polymorphonuclear cells. J
Lipid Mediat Cell Signal. 1994 May;9(3):285-90. Petit P, Sauvaire Y,
Ponsin G, Manteghetti M, Fave A, Ribes
G. Effects of a fenugreek seed extract on feeding behaviour
in the rat: metabolic-endocrine correlates. Pharmacol
Biochem Behav. 1993 Jun;45(2):369-74. |
||||||
|
Prager N, Bickett K,
French N, Marcovici G. A randomized, double-blind,
placebo-controlled trial to determine the effectiveness of botanically derived
inhibitors of 5-alpha-reductase in the treatment of androgenetic
alopecia. J Altern Complement Med. 2002 Apr;8(2):143-52. Raghuram TC, Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of
Ocimum sanctum leaf extract. J Ethnopharmacol.
1990 Feb;28(2):143-50. Sarkar A, |
||||||
|
Schulze-Tanzil G, de
SP, Behnke B, Klingelhoefer
S, Scheid A, Shakibaei M.
Effects of the antirheumatic remedy hox alpha--a new stinging nettle leaf extract--on matrix metalloproteinases in human chondrocytes
in vitro. Histol Histopathol.
2002 Apr;17(2):477-85. Sembulingam K, Sembulingam
P, Namasivayam A. Effect of Ocimum
sanctum Linn on noise induced changes in plasma corticosterone
level.Indian J Physiol Pharmacol. 1997 Apr;41(2):139-43. Sen P, Maiti
PC, Puri S, Ray A, Audulov
NA, Valdman AV Mechanism of anti-stress activity of
Ocimum sanctum Linn, eugenol
and Tinospora malabarica
in experimental animals. Indian J Exp Biol. 1992 Jul;30(7):592-6. Sharma RD, Raghuram
TC, |
||||||
|
Singh
S, Majumdar DK. Effect of Ocimum
sanctum fixed oil on vascular permeability and leucocytes migration. Indian J
Exp Biol. 1999 Nov;37(11):1136-8. Stark
A, Madar Z. The effect of an ethanol extract
derived from fenugreek (Trigonella foenum-graecum) on bile acid absorption and cholesterol
levels in rats.Br J Nutr. 1993 Jan;69(1):277-87. Sur P, Das
M, Gomes A, Vedasiromoni JR, Sahu
NP, Banerjee S, Sharma RM, Ganguly
DK. Trigonella foenum graecum (fenugreek) seed extract as an antineoplastic agent. Phytother
Res. 2001 May;15(3):257-9. Urman B, Pride SM, Yuen BH.
Elevated serum testosterone, hirsutism, and virilism
associated with combined androgen-estrogen hormone replacement therapy. Obstet Gynecol. 1991 Apr;77(4):595-8. |
||||||
|
|
||||||
|
♦These statements have not been evaluated by the
Food and Drug Administration. This product is not
intended to diagnose, treat, cure or prevent any disease. |
||||||
|
|
||||||
|
Formulated by: YourMenopauseType.com, Inc. www.YourMenopauseType.com |
||||||
|
|
||||||
|
YourMenopauseType.com, Inc. |
||||||
